Wednesday, 16 May 2012

All Nobel Prizes


All Nobel Prizes

2011

THE NOBEL PRIZE IN PHYSICS
Saul Perlmutter, Brian P. Schmidt, Adam G. Riess
THE NOBEL PRIZE IN PHYSIOLOGY OR MEDICINE
Bruce A. Beutler, Jules A. Hoffmann, Ralph M. Steinman
THE NOBEL PEACE PRIZE
Ellen Johnson Sirleaf, Leymah Gbowee, Tawakkol Karman
THE PRIZE IN ECONOMIC SCIENCES
Thomas J. Sargent, Christopher A. Sims

2010

THE NOBEL PRIZE IN PHYSICS
Andre Geim, Konstantin Novoselov
THE NOBEL PRIZE IN CHEMISTRY
Richard F. Heck, Ei-ichi Negishi, Akira Suzuki
THE PRIZE IN ECONOMIC SCIENCES
Peter A. Diamond, Dale T. Mortensen, Christopher A. Pissarides

2009

THE NOBEL PRIZE IN PHYSICS
Charles Kuen Kao, Willard S. Boyle, George E. Smith
THE NOBEL PRIZE IN CHEMISTRY
Venkatraman Ramakrishnan, Thomas A. Steitz, Ada E. Yonath
THE NOBEL PRIZE IN PHYSIOLOGY OR MEDICINE
Elizabeth H. Blackburn, Carol W. Greider, Jack W. Szostak
THE NOBEL PEACE PRIZE
Barack H. Obama
THE PRIZE IN ECONOMIC SCIENCES
Elinor Ostrom, Oliver E. Williamson

2008

THE NOBEL PRIZE IN PHYSICS
Yoichiro Nambu, Makoto Kobayashi, Toshihide Maskawa
THE NOBEL PRIZE IN CHEMISTRY
Osamu Shimomura, Martin Chalfie, Roger Y. Tsien
THE NOBEL PRIZE IN PHYSIOLOGY OR MEDICINE
Harald zur Hausen, Françoise Barré-Sinoussi, Luc Montagnier
THE NOBEL PRIZE IN LITERATURE
Jean-Marie Gustave Le Clézio
THE NOBEL PEACE PRIZE
Martti Ahtisaari

NIPER JEE Questions :

Which fatty is biosynthesized by human body(N-10)
a)Stearic acid
b)Oleic acid
c)Linoleic acid
d)Linolenic acid

RBI nationalized in(N-09)
a)1951
b)1950
c)1949
d)1935

When HBr is added to styrene according to antimarkonikove rule,what product?(N-2010)
a)C6H5CHBrCH3
b)C6H5CH2CH2Br
c)C6H5CH2CH3
d) None of these

In which State AYUSH (AYURVEDIC, YOGA, UNANI, HOMOPATHY,) is established?(N-10)
a) Himachal Pradesh
b) Utterakhand
c) Kerla
d) M.P

Which of the following alpha glucosidase inhibitor is polysaccharide?(N)
(a)miglitol
(b)viglibiose
(c)acarbose
(d) glucogol.

Which receptor has heptahelical structure? (N)
(a) metabotropic
(b)tyrosine kinase
(c)ionotropic
(d)nuclear

Which of the following is inverse agonist? (N)
(a) beta carboline
(b)cannabinoids
(c)none of the above
(d)all of the above

Which of the following cephalosporin has disulfiram like effect? (N)
(a) cefixime
(b) cefaperazone
(c) cefuroxime
(d)cefamandole

Full forms List



Full Form List :
UDV Unit Dose Vial
UKECA United Kingdom Ethics Committee Authority
USP United States Pharmacopoeia
WIPO World Intellectual Patent Office
TGA Therapeutic Goods Administration, Australia

TMF Trial Master File
SARS Severe Acute Respiratory Syndrome
SCDM Society for Clinical Data Management
SIDS Sudden Infant Death Syndrome
SIGAR Special Interest Group on Adverse Reactions
R&D Research and Development
RAPS Regulatory Affairs Professionals Society
RCT Randomised Clinical Trials
RDE Remote Data Entry
RDS Research Defence Society
REC Research Ethics Committee
RGN Registered General Nurse
RPSGB Royal Pharmaceutical Society of Great Britain
RSM Royal Society of Medicine
Rx Prescription
QA Quality Assurance

QSM-WHO Quality Assurance and Safety of Medicines (WHO)
PDS Pharmacoepidemiology and Drug Safety (journal)

PEM Prescription Event Monitoring

PHRMA Pharmaceutical Research and Manufacturers Association

PIL Package Insert Leaflet
PMDA Pharmaceuticals and Medical Devices Agency, Japan

PMS Post-Marketing Surveillance

POM Prescription Only Medicine

PSM Procurement and Supply Management

PSUR Periodic Safety Update Report
NAFDAC National Agency for Food and Drug Administration and Control, Nigeria
NCPA National Community of Pharmacist Association
NCPO National Conference of Pharmaceutical Organisations
NDA New Drug Application
NDMS National Disaster Medical System
NME New Molecule Entity
NSAID Non-Steroidal Anti-Inflammatory Drug
IACUC Institutional Animal Care and Use Committee
IAES Institutional Animal Ethics Committee
ICDRA International Conference for Drug Regulatory Authorities
ICH International Conference on Harmonization
IIG Inactive Ingredient Guide 
IMP Investigational Medicinal Products IMP - Investigational Medicinal Products
IMPD Investigational Medicinal Product Dossier
INDA Investigational New Drug Application
INN International non-proprietary names (for pharmaceutical substances)
INTDIS International Drug Information System - the previous WHO adverse reactions database
IPC Indian Pharmaceutical Congress
IPGA Indian Pharmacy Graduate Association
ISO International Organization for Standardization
ISoP International Society of Pharmacovigilance
ISPE International Society for Pharmacoepidemiology
HIS Indian Health Services 
HPLC High Performance Liquid Chromatography
HRSA Health Resources & Service Administration
GCP Good Clinical Practices
GLP Good Laboratory Practices
GMP Good Manufacturing Practices
FDA Food & Drug Administration
FIP International Pharmaceutical Federations
DRA Drug Regulatory Affairs
DUMP Disposal of Unwanted Medicines and Poisons
CADD Computer Aided Drug Design
CDC Centre for Disease Control
CIOMS Council for International Organisations of Medical Sciences
CPCSEA Committee for Purpose of Control & Supervision of Experimental Animals
CPI Consumer Price Index 
CRA Clinical Research Associate
CRC Clinical Research Council
CRF Case Report Form
CRN Clinical Research Network
CRO Contract Research Organisation
CSM Committee on Safety of Medicine
CTC Clinical Trials Centre
BMA British Medical Association
BMJ British Medical Journal
BPC Bulk Pharmaceutical Chemicals
BPI British Pharmaceutical Index
BrAPP British Association of Pharmaceutical Physicians
AAAS American Association of Advancement of Science
AALAS American Association for Laboratory Animal Science
AIDS Acquired Immune Deficiency Syndrome 
AIOPI Association of Information Officers of the Pharmaceutical Industry
ALF American Liberation Front
ANDA Abbreviated New Drug Application

Intellectual Property Rights:

 Intellectual Property Rights: Some Imp Points



  • A patent is an exclusive right granted for an invention, which is a product or a process that provides, in general, a new way of doing something, or offers a new technical solution to a problem.  In order to be patentable, the invention must fulfill certain conditions.
  • Trademarks are distinctive signs, used to differentiate between identical or similar goods and services offered by different producers or services providers. Trademarks are a type of industrial property, protected by intellectual property rights. 
  • An industrial design is the ornamental or aesthetic aspect of an article. The design may consist of three-dimensional features, such as the shape or surface of an article, or of two-dimensional features, such as patterns, lines or color.
  • geographical indication (GI) is a sign used on goods that have a specific geographical origin and possess qualities, reputation or characteristics that are essentially attributable to that origin. An appellation of origin (AO) is a special kind of GI.
  • Copyright and related rights protect the rights of authors, performers, producers and broadcasters, and contribute to the cultural and economic development of nations. This protection fulfills a decisive role in articulating the contributions and rights of different stakeholders and the relation between them and the public. The purpose of copyright and related rights is twofold: to encourage a dynamic creative culture, while returning value to creators so that they can lead a dignified economic existence, and to provide widespread, affordable access to content for the public.

FDA Approval Drugs-2012


FDA Approval Drugs-2012
Dermatology/Plastic Surgery
Erivedge (vismodegib); Genentech; For the treatment of basal cell carcinoma, Approved January 2012
Picato (ingenol mebutate) gel; LEO Pharma; For the treatment of actinic keratosis, Approved January 2012
Sklice (ivermectin) lotion; Sanofi Pasteur; For the treatment of head lice, Approved February 2012
Endocrinology
Bio-T-Gel (testosterone gel); Teva Pharmaceuticals; For the treatment of hypogonadism, Approved February 2012
Elelyso (taliglucerase alfa); Pfizer Inc; For the treatment of Gaucher disease, Approved May 2012
Jentadueto (linagliptin plus metformin hydrochloride); Eli Lilly; For the treatment of type II diabetes, Approved February 2012
Korlym (mifepristone); Corcept Therapeutics; For the control of hyperglycemia in adults with endogenous Cushing’s syndrome, Approved February 2012
Ultresa (pancrelipase) delayed-release capsules; Aptalis Pharma; For the treatment of exocrine pancreatic insufficiency due to cystic fibrosis or other conditions, Approved March 2012
Viokace (pancrelipase) tablets; Aptalis Pharma; For the treatment of exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatectomy, Approved March 2012
Gastroenterology
Elelyso (taliglucerase alfa); Pfizer Inc; For the treatment of Gaucher disease, Approved May 2012
Ultresa (pancrelipase) delayed-release capsules; Aptalis Pharma; For the treatment of exocrine pancreatic insufficiency due to cystic fibrosis or other conditions, Approved March 2012
Viokace (pancrelipase) tablets; Aptalis Pharma; For the treatment of exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatectomy, Approved March 2012
Hematology
Elelyso (taliglucerase alfa); Pfizer Inc; For the treatment of Gaucher disease, Approved May 2012
Omontys (peginesatide); Affymax; For the treatment of anemia due to chronic kidney disease, Approved March 2012
Immunology/Infectious Diseases
Qnasl (beclomethasone dipropionate) nasal aerosol; Teva Pharmaceuticals; For the treatment of seasonal and perennial allergic rhinitis, Approved March 2012
Musculoskeletal
Elelyso (taliglucerase alfa); Pfizer Inc; For the treatment of Gaucher disease, Approved May 2012
Neupro (Rotigotine Transdermal System); UCB; For the treatment of Restless Legs Syndrome, Approved April 2012
Stendra (avanafil); Vivus; For the treatment of erectile dysfunction, Approved April 2012
Votrient (pazopanib); GlaxoSmithKline; For the treatment of soft tissue sarcoma, Approved April 2012
Nephrology/Urology
Afinitor (everolimus); Novartis Pharmaceuticals Corporation; For the treatment of renal angiomyolipoma associated with tuberous sclerosis complex, Approved April 2012
Inlyta (axitinib); Pfizer; For the treatment of advanced renal cell carcinoma, Approved January 2012
Omontys (peginesatide); Affymax; For the treatment of anemia due to chronic kidney disease, Approved March 2012
Stendra (avanafil); Vivus; For the treatment of erectile dysfunction, Approved April 2012
Voraxaze (glucarpidase); BTG International; For the treatment of toxic plasma methotrexate concentrations in patients with impaired renal function, Approved January 2012
Neurology
Neupro (Rotigotine Transdermal System); UCB; For the treatment of Restless Legs Syndrome, Approved April 2012
Subsys (fentanyl sublingual spray); Insys Therapeutics; For the treatment of breakthrough cancer pain, Approved January of 2012
Obstetrics/Gynecology
Natazia (estradiol valerate and estradiol valerate/dienogest); Bayer HealthCare; For the treatment of heavy menstrual bleeding, Approved March 2012
Oncology
Afinitor (everolimus); Novartis Pharmaceuticals Corporation; For the treatment of renal angiomyolipoma associated with tuberous sclerosis complex, Approved April 2012
Erivedge (vismodegib); Genentech; For the treatment of basal cell carcinoma, Approved January 2012
Inlyta (axitinib); Pfizer; For the treatment of advanced renal cell carcinoma, Approved January 2012
Picato (ingenol mebutate) gel; LEO Pharma; For the treatment of actinic keratosis, Approved January 2012
Subsys (fentanyl sublingual spray); Insys Therapeutics; For the treatment of breakthrough cancer pain, Approved January of 2012
Votrient (pazopanib); GlaxoSmithKline; For the treatment of soft tissue sarcoma, Approved April 2012
Ophthalmology
Zioptan (tafluprost ophthalmic solution); Merck; For the treatment of elevated intraocular pressure, Approved February 2012
Otolaryngology
Dymista (azelastine hydrochloride and fluticasone propionate); Meda Pharmaceuticals Inc.; For the relief of symptoms of seasonal allergic rhinitis, Approved May 2012
Qnasl (beclomethasone dipropionate) nasal aerosol; Teva Pharmaceuticals; For the treatment of seasonal and perennial allergic rhinitis, Approved March 2012
Pediatrics/Neonatology
Qnasl (beclomethasone dipropionate) nasal aerosol; Teva Pharmaceuticals; For the treatment of seasonal and perennial allergic rhinitis, Approved March 2012
Sklice (ivermectin) lotion; Sanofi Pasteur; For the treatment of head lice, Approved February 2012
Surfaxin (lucinactant); Discovery Laboratories; For the treatment of respiratory distress syndrome in premature infants, Approved March 2012
Pharmacology/Toxicology
Voraxaze (glucarpidase); BTG International; For the treatment of toxic plasma methotrexate concentrations in patients with impaired renal function, Approved January 2012
Pulmonary/Respiratory Diseases
Dymista (azelastine hydrochloride and fluticasone propionate); Meda Pharmaceuticals Inc.; For the relief of symptoms of seasonal allergic rhinitis, Approved May 2012
Kalydeco (ivacaftor); Vertex Pharmaceuticals; For the treatment of cystic fibrosis with the G551D mutation in the CFTR gene, Approved January of 2012
Qnasl (beclomethasone dipropionate) nasal aerosol; Teva Pharmaceuticals; For the treatment of seasonal and perennial allergic rhinitis, Approved March 2012
Surfaxin (lucinactant); Discovery Laboratories; For the treatment of respiratory distress syndrome in premature infants, Approved March 2012
Rheumatology
Stendra (avanafil); Vivus; For the treatment of erectile dysfunction, Approved April 2012

List of Laboratories in INDIA


§  BCG Vaccine Lab- Chennai
§  Central drug testing lab- Mumbai
§  Central drug Laboratory- Kolkatta
§  Central Drug Research Institute - Lucknow
§  Central Research Institute- Kasauli
§  Indian Drug Manufactures Association- Mumbai
§  Indian Society of Blood Trensfusion & Immunoheamatology- Pune
§  Indian Veterinary Research Institute- Izatnagar
§  Central Indian Pharmacoepia Laboratory- Ghaziabad
§  National Plasma Fractionation Centre- Mumbai
§  National Institute for Communicable Disease- New Delhi
§  Indian Institute for Virology- Pune
§  Organization of Pharmaceutical Procedures- Mumbai
§  Dabur Research foundaion- Ghaziabad
§  Institute of applied man power research- New Delhi
§  CD Testing Lab- Mumbai
§  Synthetic Drug Plant- Hyderabad
§  National Institute of Nutrition - Hyderabad